Searchable abstracts of presentations at key conferences in endocrinology

Endocrine Abstracts

Published by BioScientifica

Page 1 of about 1 results

ea0041oc1.1 | Adrenal - Basic & Clinical | ECE2016

Genetic landscape of sporadic unilateral adrenocortical adenomas without PRKACA p.Leu206Arg mutation

Ronchi Cristina , Di Dalmazi Guido , Sbiera Silviu , Assie Guillaume , Weigand Isabel , Calebiro Davide , Appenzeller Silke , Rubin Beatrice , Waldmann Jens , Scaroni Carla , Bartsch Detlef , Mantero Franco , Mannelli Massimo , Kastelan darko , Chiodini Iacopo , Bertherat Jerome , Reincke Martin , Strom Tim , Fassnacht Martin , Beuschlein Felix

Genetic alterations affecting the PKA/cAMP pathway are commonly found in cortisol-producing adrenocortical adenomas (ACAs), while activating mutations in the gene coding for β-catenin (CTNNB1) have been reported in both adenomas and carcinomas. However, the molecular pathogenesis of most ACAs is still unclear. Aim of the study was a comprehensive genetic characterization of sporadic ACAs and the identification of novel molecular markers involved in adrenal tumori...
0 shares

Published by BioScientifica

Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
© Bioscientifica 2024 | Privacy policy | Cookie settings

BiosciAbstracts

Bioscientifica Abstracts is the gateway to a series of products that provide a permanent, citable record of abstracts for biomedical and life science conferences.

Find out more